
Sickle Cell
disease affects more than 50,000 Americans. It is also found in
individuals from the Mediterranean, the Caribbean and Africa.
1 in
375 African American children is born with sickle cell disease.
1 in 10 African American children is born with sickle cell
trait.

Sickle cell
disease is not contagious. It is an inherited disorder which causes
the red blood cells to change from their soft, round shape to a
long, hard "sickle" or crescent shape.
Sickle-shaped
red blood cells are stiff. They often clog the body's blood
vessels, blocking the flow of blood and oxygen and causing pain.
The tissue eventually becomes damaged. This is what causes the complications
of sickle cell disease. Click the button below for an animated
demonstration ( You must have the FLASH
plug-in installed on your browser to view this animation ).


Sickle cell
trait is not a disease at all. People born with sickle cell trait
are not sick. They do not have the pain or anemia associated with
sickle cell disease. Under normal conditions, their red blood cells
remain round and flexible. However, they may have a child with sickle
cell disease.
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